The label says, word for word:
PrednisTab is intended for use in dogs. The indications for PrednisTab are the same as those for other anti-inflammatory steroids and comprise the various collagen, dermal, allergic, ocular, otic, and musculoskeletal conditions known to be responsive to the anti-inflammatory corticosteroids.
Do not use in viral infections. Prednisolone, like methylprednisolone, is contraindicated in animals with peptic ulcer, corneal ulcer, and Cushingoid syndrome. The presence of diabetes, osteoporosis, predisposition to thrombophlebitis, hypertension, congestive heart failure, renal insufficiency, and active tuberculosis necessitates carefully controlled use.
Not for human use.
Clinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition if used during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis.
Additionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia, and anasarca.
Because of its inhibitory effect on fibroplasia, prednisolone may mask the signs of infection and enhance dissemination of the infecting organism. Hence, all animal patients receiving prednisolone should be watched for evidence of intercurrent infection.
Since prednisolone, like methylprednisolone, suppresses endogenous adrenocortical activity, it is highly important that the animal patient receiving prednisolone be under careful observation, not only during the course of treatment but for some time after treatment is terminated.
Every approved medicine has a field study behind it, and the label prints what happened:
Side effects, such as SAP and SALT enzyme elevations, weight loss, anorexia, polydipsia and polyuria have occurred following the use of synthetic cortico-steroids in dogs. Vomiting and diarrhea (occasionally bloody) have also been observed. Cushing's syndrome in dogs has been reported in association with prolonged or repeated steroid therapy. (The label gives no percentages.)
The page slug is "prednisone", but the label used is an FDA-approved VETERINARY prednisolone product: "PREDNISTAB (prednisolone tablets), USP", "For Oral Use in Dogs Only", "Approved by FDA under NADA # 140-921", "Federal law restricts this drug to use by or on the order of a licensed veterinarian." A human label was therefore not used. DailyMed lists four PrednisTab labels (LLOYD, Inc. of Iowa; Vedco Inc.; Butler Animal Health Supply, LLC; Clipper Distributing Company LLC); the LLOYD label is quoted here.
The emergency page sorts the signs by how long you have, and the symptom checker asks what you are seeing. Reactions to a medicine can also be reported to the FDA yourself: how to report a problem.
These answers come from the approved label on DailyMed, read on 2 October 2026. Where the label does not say, the answer says so, and the vet or the pharmacist is the one to ask.
The approved use is quoted at the top of this page. The label read for these answers is the one for PrednisTab, prednisolone tablets for dogs. It is a steroid given against inflammation in conditions of the skin, eyes, ears, muscles and joints, and in allergic reactions.
The label says the starting dose is kept up until the dog responds well, which it says usually takes 2 to 7 days in muscle and joint disease, in allergic conditions of the skin or the airways, and in inflamed eyes. If there is no satisfactory response in 7 days, the label says the case should be looked at again.
The tablets are given by mouth. The label says the day's amount is split into equal doses instead of being given all at once, and that once the dog has responded the dose is reduced gradually, and slowly in long-running conditions. The label gives the dose by weight, which the vet works out; it does not say whether to give it with food.
The label does not say what to do about a missed dose. Call the clinic or the pharmacy before you give the next one.
The studies and the warnings are quoted above. The label has no line telling owners when to call the vet. It does say a dog on prednisolone should be watched carefully during the course and for some time after it ends, and watched for signs of infection, because the drug can mask them. If your dog seems unwell while taking it or after the course ends, call the vet.
Store the tablets at room temperature, between 68° and 77°F; the label allows short spells between 59° and 86°F.
The FDA says the best way to get rid of most unused or expired medicines is a take-back option: a drug take-back location, which can be at a pharmacy or a police station, or a prepaid mail-back envelope. If you cannot use one and the medicine is not on the FDA's flush list, the FDA says to mix it, uncrushed, with something unappealing such as dirt, cat litter or used coffee grounds and to seal the mixture in a plastic bag before throwing it away. Flushing is only for medicines on that list, such as opioids. Do not give leftovers to another pet.
Write the dose, the times and the stop date here, then print this page for the fridge.
Dose and times: _____________________________________________
Stop date: _____________________________________________