The label says, word for word:
Entyce: "ENTYCE (capromorelin oral solution) is indicated for appetite stimulation in dogs." Elura: "For management of weight loss in cats with chronic kidney disease."
ENTYCE should not be used in dogs that have a hypersensitivity to capromorelin. ELURA should not be used in cats that have a hypersensitivity to capromorelin.
Not for use in humans. Keep this drug, including used syringes, out of reach of children. Wash hands immediately after use as this product may be dermally absorbed. Consult a physician in case of accidental ingestion by humans.
Keep ENTYCE in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
Use with caution in dogs that may have cardiac disease or severe dehydration. ENTYCE can cause transient decreases in heart rate and blood pressure following dose administration. Some dogs may exhibit clinical signs of bradycardia or hypotension following administration of ENTYCE (See Post-Approval Experience).
Use with caution in dogs with diabetes mellitus as hyperglycemia has been reported following administration of ENTYCE (See Post-Approval Experience).
Elura: Do not use in cats with hypersomatotropism (acromegaly). ELURA may increase serum glucose for several hours after dosing. Use in cats with current or historical diabetes mellitus has not been evaluated and use may not be appropriate.
Every approved medicine has a field study behind it, and the label prints what happened:
Entyce, controlled field study (ENTYCE n = 171, n (%)): Diarrhea 12 (7.0%); Vomiting 11 (6.4%); Elevated blood urea nitrogen 7 (4.1%); Polydipsia 7 (4.1%); Hypersalivation 4 (2.3%); Elevated phosphorus 4 (2.3%); Abdominal discomfort 2 (1.2%); Flatulence 2 (1.2%); Nausea 2 (1.2%); Lethargy/depression 2 (1.2%).
Entyce: Approved by FDA under NADA # 141-457; original approval May 16, 2016 (original sponsor Aratana Therapeutics, Inc.; now Elanco US Inc.); label revised August 2025; "For use in dogs only." Elura: Approved by FDA under NADA # 141-536; original approval October 16, 2020 (FOI summary); "For oral use in cats only."; label revised 08/2025. Elura precautions, verbatim: "Use with caution in cats that may have cardiac disease or severe dehydration."
The emergency page sorts the signs by how long you have, and the symptom checker asks what you are seeing. Reactions to a medicine can also be reported to the FDA yourself: how to report a problem.
These answers come from the approved label on DailyMed, read on 2 October 2026. Where the label does not say, the answer says so, and the vet or the pharmacist is the one to ask.
The approved use is quoted at the top of this page. It is a flavored liquid given by mouth to stimulate a dog's appetite. The label read for these answers is the Entyce label, which is for dogs. Elura, the same drug for cats, has a label of its own, which is in the sources below.
The label gives no time for when a dog should start eating more. It says the drug is absorbed rapidly and reaches its highest level in the blood within 0.83 hours, which is about 50 minutes. In the field study on the label the dogs were treated for 4 days, and their owners judged their appetite at the start and again around day 3. The label says Entyce has not been tested beyond 4 days of treatment in that study. Ask the vet what to expect and by when.
It is a liquid given by mouth once a day, with the dosing syringe that comes with the bottle. The label says to shake the bottle gently, push the syringe firmly into the opening of the bottle, turn the bottle upside down and draw up the amount the vet prescribed. Turn the bottle upright again before you take the syringe out, put the cap back on, and give the liquid into the dog's mouth. Rinse the syringe and its plunger with water between doses and leave them apart to dry. Wash your hands straight after, because the label says the product may be absorbed through the skin. The label does not say whether to give it with food.
The label does not say what to do about a missed dose. Call the clinic or the pharmacy before you give the next one.
The studies and the warnings are quoted above. The label has no line telling owners when to call the vet. It tells vets to use Entyce with caution in dogs with liver or kidney problems, dogs that may have heart disease or severe dehydration, and dogs with diabetes. If your dog seems unwell while on it, call the vet. If a person swallows it, the label says to consult a physician.
Store it at or below 86°F. The label says to keep the drug, including used syringes, out of the reach of children. It also says to keep it in a secure place out of reach of dogs, cats and other animals, to prevent accidental swallowing or an overdose.
The FDA says the best way to get rid of most unused or expired medicines is a take-back option: a drug take-back location, which can be at a pharmacy or a police station, or a prepaid mail-back envelope. If you cannot use one and the medicine is not on the FDA's flush list, the FDA says to mix it with something unappealing such as dirt, cat litter or used coffee grounds and to seal the mixture in a plastic bag before throwing it away. Flushing is only for medicines on that list, such as opioids. Do not give leftovers to another pet.
Write the dose, the times and the stop date here, then print this page for the fridge.
Dose and times: _____________________________________________
Stop date: _____________________________________________