The label says, word for word:
Drontal (praziquantel/pyrantel pamoate) tablets will remove Tapeworms (Dipylidium caninum, Taenia taeniaeformis), Hookworms (Ancylostoma tubaeforme), and Large Roundworms (Toxocara cati) in cats and kittens.
DO NOT USE IN PREGNANT ANIMALS.
The effects of Drontal Plus on pregnant animals have not been determined.
There are no known contraindications against the use of praziquantel or pyrantel pamoate in dogs.
KEEP OUT OF REACH OF CHILDREN. Consult your veterinarian before administering to sick or pregnant animals.
NOT FOR USE IN KITTENS LESS THAN TWO MONTHS OF AGE OR WEIGHING LESS THAN 2 LBS.
NOT FOR USE IN PUPPIES LESS THAN 3 WEEKS OF AGE OR DOGS WEIGHING LESS THAN 2 LBS.
Strict hygienic precautions should be taken when handling dogs or feces suspected of harboring E. multilocularis.
Every approved medicine has a field study behind it, and the label prints what happened:
Post-Approval Experience: Although not all adverse reactions are reported, based on voluntary post-approval reporting, transient ataxia has been reported following the administration of Drontal Tablets for Cats and Kittens.
None of the 103 dogs treated with Drontal Plus Anthelmintic Tablets in the clinical field studies exhibited drug-related side effects.
Drontal for cats: 'Approved by FDA under NADA # 141-008'; DailyMed classes it as an OTC animal drug label and it carries no 'Federal law restricts' statement; the FOI summary for NADA 141-008 (original sponsor Miles Inc.) prints no approval date, so the year is not known from allowed sources. Drontal Plus for dogs: 'Approved by FDA under NADA number 141-007' (FOI 'Approval Date: May 19, 1994', sponsor Miles, Inc.) and carries 'CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.'; DailyMed setid 9ccf3782-220d-4e8e-95d0-8e79a9a909ae.
The emergency page sorts the signs by how long you have, and the symptom checker asks what you are seeing. Reactions to a medicine can also be reported to the FDA yourself: how to report a problem.
These answers come from the approved label on DailyMed, read on 2 October 2026. Where the label does not say, the answer says so, and the vet or the pharmacist is the one to ask.
The approved use is quoted at the top of this page. It is a deworming tablet that removes tapeworms, hookworms and large roundworms. The label read for these answers is the one for cats and kittens, and it says the tablets are not for kittens under two months of age or under 2 pounds. Drontal Plus, the tablet for dogs, has a label of its own, which is in the sources below.
The label says large roundworms and hookworms may be seen in the cat's stool a day or so after the tablet. It says most tapeworms are digested, so they are not found in the stool after treatment.
The label says the tablet may be given directly by mouth or offered in a small amount of food, and that food should not be withheld from the cat before or after treatment. It says to weigh the cat first, because the number of whole or part tablets goes by body weight. The tablets are scored so that they break easily.
The label does not say what to do about a missed dose. Call the clinic or the pharmacy before you give the next one. On giving it again, the label says treatment may be repeated if the cat picks up worms again. It says a cat that is constantly exposed to worms should have a follow-up stool test within 2 to 4 weeks of the first treatment, and that tapeworms carried by fleas will likely come back unless the fleas are controlled. Petipedia has pages on worms and on fleas.
The studies and the warnings are quoted above. The label has no line telling owners when to call the vet. It does say to consult your veterinarian before giving the tablets to a sick or pregnant animal. If your cat seems unwell after the tablet, call the vet.
Store it between 68° and 77°F; the label allows short spells between 59° and 86°F, and it says exposure to heat up to 104°F should be brief and kept to a minimum. Keep it out of the reach of children.
The FDA says the best way to get rid of most unused or expired medicines is a take-back option: a drug take-back location, which can be at a pharmacy or a police station, or a prepaid mail-back envelope. If you cannot use one and the medicine is not on the FDA's flush list, the FDA says to mix it, uncrushed, with something unappealing such as dirt, cat litter or used coffee grounds and to seal the mixture in a plastic bag before throwing it away. Flushing is only for medicines on that list, such as opioids. Do not give leftovers to another pet.
Write the dose, the times and the stop date here, then print this page for the fridge.
Dose and times: _____________________________________________
Stop date: _____________________________________________