The label says, word for word:
Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (Asian longhorned tick)] for 12 weeks in dogs and puppies 6 months of age and older,…
There are no known contraindications for the use of the product.
Fluralaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures.
Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders.
Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.
Adverse events have been reported following use in breeding females. Before use in breeding female dogs, refer to Post-Approval Experience and Animal Safety sections.
Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age.
Every approved medicine has a field study behind it, and the label prints what happened:
The most frequently reported adverse reaction in dogs in the Bravecto and active control groups was vomiting.
Dog chew field study table (Bravecto group): Vomiting 7.1%; Decreased Appetite 6.7%; Lethargy 5.4%; Diarrhea 4.9%; Polydipsia 1.8%; Flatulence 1.3%
In a well-controlled U.S. field study, which included a total of 161 households and 311 treated cats (224 with fluralaner and 87 with a topical active control), there were no serious adverse reactions.
Bravecto chew: Approved by FDA under NADA 141-426 (FOI 'Date of Approval: May 25, 2014', sponsor Intervet, Inc.). Bravecto topical solution for dogs and for cats: 'Approved by FDA under NADA # 141-459'. Cat topical label indication (verbatim): 'Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) for 12 weeks in cats and kittens 12 weeks of age and older, and weighing 2.6 pounds or greater.' with tick claims only for 'cats and kittens 6 months of age and older'.
The emergency page sorts the signs by how long you have, and the symptom checker asks what you are seeing. Reactions to a medicine can also be reported to the FDA yourself: how to report a problem.
These answers come from the approved label on DailyMed, read on 2 October 2026. Where the label does not say, the answer says so, and the vet or the pharmacist is the one to ask.
The approved use is quoted at the top of this page. It is a chew that kills adult fleas, treats and prevents flea infestations and treats and controls tick infestations for 12 weeks at a time, or for 8 weeks in the case of the lone star tick. It is for dogs and puppies that are six months or older and weigh at least 4.4 pounds. The label read for these answers is the one for the chew for dogs. The Bravecto liquids that go on the skin of dogs and of cats have labels of their own.
The label says Bravecto began to kill fleas within two hours of being given in a laboratory study. In a European laboratory study it cut the number of live fleas, and of one kind of tick, by more than 98% within 12 hours.
It is given by mouth as a single dose every 12 weeks, and the label says it should be given with food. The label allows a dose every 8 weeks where lone star ticks are a risk. It says treatment may begin at any time of the year and can continue all year round. Keep the chew in its original packaging until you use it, and do not eat, drink or smoke while handling it. Wash your hands with soap and water straight afterwards.
The label does not say what to do about a missed dose. Call the clinic or the pharmacy before you give the next one.
The studies and the warnings are quoted above. The label has no line telling owners when to call the vet. It does say that drugs of this class have been linked to tremors, unsteady walking and seizures, and that seizures have been reported even in dogs with no history of them. Call the vet straight away if you see any of these.
The label says not to store it above 86°F. It says to keep the chews in the original packaging until use, so that children cannot get at them, and in a secure place out of reach of dogs, cats and other animals.
The FDA says the best way to get rid of most unused or expired medicines is a take-back option: a drug take-back location, which can be at a pharmacy or a police station, or a prepaid mail-back envelope. If you cannot use one and the medicine is not on the FDA's flush list, the FDA says to mix it, uncrushed, with something unappealing such as dirt, cat litter or used coffee grounds and to seal the mixture in a plastic bag before throwing it away. Flushing is only for medicines on that list, such as opioids. Do not give leftovers to another pet.
Write the dose, the times and the stop date here, then print this page for the fridge.
Dose and times: _____________________________________________
Stop date: _____________________________________________