Eye ulcer in dogs and cats: the squint, the green dye test and the drops that make it worse

An eye ulcer is a scratch or sore through the clear front layer of the eye, the cornea. In dogs it is usually an injury: a claw, a stick, a rub along the carpet, rough play with another animal. In cats it is usually the herpes virus. Most heal within days on the right drops. The ones that go wrong do it fast, and one of the ways owners make an ulcer worse is with the wrong eye medicine from the cupboard. Everything here comes from the veterinary ophthalmologists' college, the Merck Veterinary Manual, Cornell's feline health center and two studies of which dogs get ulcers, and each is linked at the bottom.

About 1 in 125dogs in England had an eye ulcer in a single year, in a study of more than 100,000 dogs19 timesthe risk for a Pug, compared with a crossbred dog, in the same study11 timesthe risk for the flat-faced breeds as a group3 to 5 dayshow long most ulcers take to heal, according to the ophthalmologists' college

What you see

The signs are the same in dogs and cats: squinting, an eye held half or fully closed, tears or a sticky discharge, rubbing the eye with a paw or along the carpet, redness, a cloudy look to the front of the eye, and turning away from bright light.

Most pets will squint or keep their eye partially or completely closed.American College of Veterinary Ophthalmologists, Corneal ulcers, for pet owners

An ulcer usually cannot be seen without a test, so a squint is worth a call to the vet the same day. The ophthalmologists' college gives the reason in one line.

Ulcers can worsen rapidly and become serious vision threatening issues.American College of Veterinary Ophthalmologists, Corneal ulcers, for pet owners

What the vet does

The test is simple. The vet puts a drop of an orange dye called fluorescein on the eye. The dye sticks wherever the surface is broken and glows green under a blue light, so an ulcer shows up as a green patch.

A simple ulcer is treated with antibiotic drops or ointment, often every four to six hours, something for the pain, and a cone so the eye cannot be rubbed. Merck mentions atropine drops, which widen the pupil and ease the ache. The vet repeats the dye test to confirm the ulcer has closed, and the drops continue until then, even once the eye looks better. VCA's advice is never to stop them without the vet's approval.

Most corneal ulcers should heal within 3-5 days unless there is some anatomical issue causing chronic irritation or underlying bacterial, fungal or viral infection interfering with the healing process.American College of Veterinary Ophthalmologists, Corneal ulcers, for pet owners

The drops that make it worse

Corticosteroids are contraindicated both topically and systemically when a corneal ulcer is present.Merck Veterinary Manual, Anti-inflammatory agents for the eye, updated September 2024
However, glucocorticoids also inhibit epithelial regeneration and can augment the action of collagenase, leading to a melting corneal ulcer.Merck Veterinary Manual, Anti-inflammatory agents for the eye, updated September 2024

In plain words: steroids stop the surface from growing back and help the enzymes that dissolve the cornea, which is how a small ulcer becomes a melting one.

Why flat-faced dogs get them far more often

The VetCompass study at the Royal Veterinary College went through a year of records for 104,233 dogs at 110 practices in England. About 1 dog in 125 had an eye ulcer that year. The breeds at the top of the list are the ones with short noses and prominent eyes.

BreedHad an eye ulcer that yearAgainst a crossbred dog
Pugabout 1 in 18over 19 times the risk
Boxerabout 1 in 2012 times the risk
Shih Tzuabout 1 in 2910 times the risk
Cavalier King Charles Spanielabout 1 in 40not given for this breed
Bulldogabout 1 in 41not given for this breed
All dogs in the studyabout 1 in 125

Flat-faced breeds as a group had over 11 times the risk of crossbred dogs, and dogs aged six to nine had about twice the odds of dogs under three.

A second study, of 700 dogs at a referral hospital in England, measured the faces. Flat-faced dogs were twenty times more likely to have an ulcer. A fold of skin over the nose made one nearly five times more likely, eye white that shows when the dog looks straight ahead nearly three times, and a wider eyelid opening raised the risk sharply. The authors' conclusion is that breeding for these faces greatly raises the risk, and that it should be discouraged.

For an owner of one of these breeds, that comes down to three things: know the signs, keep the vet's number where you can find it at night, and treat any squint as urgent.

The ulcer that will not heal

Some ulcers in dogs are shallow and simply fail to heal, or heal and come back. Vets call them indolent ulcers, or SCCEDs. Drops alone do not fix them. They turn up mostly in middle-aged and older dogs, and VCA names Golden Retrievers alongside the breed that gets them most.

They can occur in any breed, but they are most common in the Boxer.Merck Veterinary Manual, The cornea in animals, reviewed February 2023, updated July 2026

Treatment is done at the clinic: the vet removes the loose, damaged surface and then either scratches a fine grid into the cornea or polishes it with a diamond burr, to stimulate new growth. If an ulcer has not healed in a week, it is worth asking whether it is this kind.

Cats

In cats the usual cause is a virus, not a scratch.

According to Thomas Kern, DVM, associate professor of ophthalmology at Cornell University's College of Veterinary Medicine, the most frequent cause is recurrent infection with the feline herpesvirus (FHV).Cornell Feline Health Center, Corneal ulcers

The virus stays in the body and flares up again, which is why the same cat can get ulcers more than once. Treatment can add an antiviral to the antibiotics. Two cautions apply to cats in particular.

In cats, topical steroids can reactivate feline herpesvirus, resulting in corneal ulcers and in some cases a corneal sequestrum.Merck Veterinary Manual, Anti-inflammatory agents for the eye, updated September 2024
Keratotomies are not recommended in cats as they may predispose to corneal sequestration.Merck Veterinary Manual, The cornea in animals, reviewed February 2023, updated July 2026

A sequestrum is a patch of cornea that dies and turns dark. Only cats get it, most often Persians, Himalayans and Siamese, and it is treated with surgery. So the grid treatment used on Boxers is not one for a cat, and a cat's ulcer that is slow to heal is a question for a veterinary ophthalmologist.

When it is an emergency

Go the same day, or to an emergency clinic at night, if the eye gets worse on treatment, the cornea around the ulcer turns cloudy white, the ulcer looks deep, or anything bulges from the surface of the eye. Merck describes deep ulcers where the inner layer of the cornea pushes through, or the ulcer becomes a hole, and many deep ulcers need a graft of the pink tissue from around the eye to strengthen the cornea.

In an advanced case, a perforation may develop on the corneal surface, allowing drainage of the intraocular contents. This can result in blindness and even the loss of the affected eye.Cornell Feline Health Center, Corneal ulcers

What to ask the vet

Sources

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